What is regenerative therapy with PRF?

Regenerative therapy with Platelet-Rich Fibrin (PRF) is a groundbreaking approach to treating jaw joint problems. PRF is derived from your blood and contains concentrated growth factors and healing properties. When strategically applied to the jaw joint, PRF can promote tissue regeneration, reduce inflammation, and enhance the body's natural healing processes.

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How regenerative therapy with PRF works

PRF is created by drawing a small amount of blood and processing it to concentrate platelets and growth factors. This PRF is then carefully applied to the jaw joint. The growth factors in PRF stimulate tissue repair and regeneration, making it a valuable tool in addressing jaw joint issues.

The treatment experience — what to expect?

Undergoing regenerative therapy with PRF for jaw joint issues is a straightforward and minimally invasive process. Here's what you can typically expect:


Your journey begins with a consultation with our experienced team. We will diagnose your specific TMJ disorder with our advanced tools,  discuss your symptoms and goals, and determine if PRF therapy is an appropriate treatment option for you.

PRF preparation

If PRF therapy is recommended, we'll begin by drawing a small amount of your blood. This blood is then processed to create PRF, which contains the concentrated healing components necessary for treatment.


The PRF is carefully applied to the jaw joint. The application process is minimally invasive, and discomfort is typically minimal.


Following the procedure, you can resume your daily activities with little to no downtime. Any discomfort you may experience is usually mild and short-lived.


While results can vary depending on the specific TMJ disorder, many patients experience improvements in pain relief, jaw function, and reduced inflammation within a relatively short period.

PRF: The next-generation PRP formula

Platelet-Rich Fibrin (PRF) represents a significant advancement in regenerative medicine compared to traditional Platelet-Rich Plasma (PRP) treatments. While both PRP and PRF harness the healing power of your body's platelets and growth factors, there are key differences that make PRF a superior choice for regenerative therapy. PRF is a denser and more concentrated formula compared to PRP. This means it contains more platelets, growth factors, and cytokines essential for tissue regeneration and healing.

PRF forms a natural fibrin scaffold that serves as a three-dimensional support structure for cells and tissues. This fibrin matrix enhances the stability and longevity of growth factors, ensuring a sustained release over a more extended period. PRF is prepared using a straightforward and minimally processed technique. It doesn't require anticoagulants or additives, making it a pure and natural solution derived from your blood. PRF is naturally biocompatible, reducing the risk of adverse reactions or allergies.

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Regenerative therapy for jaw joint issues: PRF

The gradual release of growth factors from the fibrin matrix allows for prolonged therapeutic effects. This means that the healing process continues over an extended period, offering more sustainable results. PRF can be applied to various medical and dental conditions, including TMJ disorders, facial rejuvenation, and dental procedures. Its versatility makes it an excellent choice for addressing a wide range of health and aesthetic concerns. PRF represents a next-generation PRP formula that offers superior concentration, longevity, and biocompatibility. Its natural fibrin matrix provides essential support for tissue regeneration, making it a preferred choice for regenerative therapy across multiple medical and dental applications.

Why choose us?

At the San Francisco Center for TMJ and Sleep Apnea, we stand out as leaders in comprehensive, patient-centered care in the treatments for TMJ. Led by Dr. Amin Samadian, a renowned expert in TMJ disorders and regenerative therapies, our practice is focused on delivering the highest standard of treatment. Our commitment to a holistic approach that goes beyond traditional medical treatments sets us apart. 

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Regenerative therapy with PRF for TMJ disorders FAQ

Is regenerative therapy with PRF safe for TMJ disorders?

How long does it take to see results for TMJ issues?

Is PRF treatment painful for jaw joint issues?

Am I a candidate for regenerative therapy with PRF for my TMJ disorder?

Is a CT scan necessary for regenerative therapy with PRF?

Is regenerative therapy with PRF safe for TMJ disorders?

Yes, regenerative therapy with PRF is considered safe for addressing TMJ disorders. Since PRF is derived from your blood, there's minimal risk of allergic reactions or adverse side effects. Our experienced team ensures a safe and comfortable experience.

How long does it take to see results for TMJ issues?

Results can vary depending on the specific TMJ disorder being treated. Some patients experience immediate improvements, while others may see gradual changes over time. Our team will provide you with a clear timeline during your consultation.

Is PRF treatment painful for jaw joint issues?

The PRF treatment process is typically well-tolerated and minimally invasive. Any discomfort is usually mild and short-lived. Our priority is to ensure your comfort throughout the procedure.

Am I a candidate for regenerative therapy with PRF for my TMJ disorder?

Candidates for PRF treatment for TMJ disorders vary depending on the specific condition. During your consultation, our team will assess your TMJ disorder and determine if PRF therapy is a suitable and effective option for you.

Is a CT scan necessary for regenerative therapy with PRF?

In some cases, a CT scan may be recommended as part of the evaluation for regenerative therapy with Platelet-Rich Fibrin (PRF). CT scans offer detailed insights into craniofacial morphology, helping our specialists identify specific features associated with an increased risk of TMJ disorders. While not always mandatory, a CT scan can enhance our understanding of your condition, aiding in precise treatment planning for regenerative therapy with PRF. While CT scans provide valuable insights, a thorough evaluation for TMJ disorders involves various diagnostic methods, including clinical assessments, sleep studies, and dental evaluations. The choice of imaging modalities should be based on the specific clinical context and information needed for diagnosis and treatment planning.

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